Ribosome biogenesis and cancer
M Derenzini, L Montanaro, D Trerè - Acta histochemica, 2017 - Elsevier
There is growing evidence indicating that the human pathological conditions characterized
by an up-regulated ribosome biogenesis are at an increased risk of cancer onset. At the …
by an up-regulated ribosome biogenesis are at an increased risk of cancer onset. At the …
Nucleolar size indicates the rapidity of cell proliferation in cancer tissues
M Derenzini, D Trerè, A Pession… - The Journal of …, 2000 - Wiley Online Library
In order to define the importance of the nucleolus in tumour pathology, the relationship
between nucleolar size and function and tumour mass growth rate was studied in vivo. Ten …
between nucleolar size and function and tumour mass growth rate was studied in vivo. Ten …
[HTML][HTML] Circulating microRNAs, miR-939, miR-595, miR-519d and miR-494, identify cirrhotic patients with HCC
F Fornari, M Ferracin, D Trerè, M Milazzo, S Marinelli… - PloS one, 2015 - journals.plos.org
The performance of circulating biomarkers for the diagnosis of hepatocellular carcinoma
(HCC) is sub-optimal. In this study we tested circulating microRNAs as biomarkers for HCC …
(HCC) is sub-optimal. In this study we tested circulating microRNAs as biomarkers for HCC …
Importance of interphase nucleolar organizer regions in tumor pathology
M Derenzini, D Trerè - Virchows Archiv B, 1992 - Springer
The importance of the distribution of silverstained nucleolar organizer regions (Ag-NORs) in
interphase nuclei for diagnostic and prognostic purposes in tumor pathology has been …
interphase nuclei for diagnostic and prognostic purposes in tumor pathology has been …
Dyskerin expression influences the level of ribosomal RNA pseudo‐uridylation and telomerase RNA component in human breast cancer
…, M Calienni, J Teruya‐Feldstein, D Trerè… - The Journal of …, 2006 - Wiley Online Library
Dyskerin is a nucleolar protein, altered in dyskeratosis congenita, which carries out two
separate functions, both fundamental for proliferating cells. One function is the pseudo …
separate functions, both fundamental for proliferating cells. One function is the pseudo …
Oxidative stress EPR measurement in human liver by radical-probe technique. Correlation with etiology, histology and cell proliferation
M Valgimigli, L Valgimigli, D Trerè, S Gaiani… - Free radical …, 2002 - Taylor & Francis
The role of reactive oxygen species (ROS) in liver disease is controversial. This mostly
reflects the difficulties to quantify ROS in vivo, particularly in humans. We aimed to measure …
reflects the difficulties to quantify ROS in vivo, particularly in humans. We aimed to measure …
[HTML][HTML] Liquid biopsy in the management of breast cancer patients: where are we now and where are we going
…, D Santini, AG Corradini, C Zamagni, D Trerè… - Diagnostics, 2023 - mdpi.com
Liquid biopsy (LB) is an emerging diagnostic tool that analyzes biomarkers in the blood (and
possibly in other body fluids) to provide information about tumor genetics and response to …
possibly in other body fluids) to provide information about tumor genetics and response to …
The silver-stained proteins of interphasic nucleolar organizer regions as a parameter of cell duplication rate
D Trerè, A Pession, M Derenzini - Experimental cell research, 1989 - Elsevier
The relationship between interphasic silver-stained proteins of the nucleolar organizer
regions (Ag-NOR proteins) and cell replication rate has been studied in 13 established …
regions (Ag-NOR proteins) and cell replication rate has been studied in 13 established …
In human hepatocellular carcinoma in cirrhosis proliferating cell nuclear antigen (PCNA) is involved in cell proliferation and cooperates with P21 in DNA repair
L Gramantieri, D Trerè, P Chieco, M Lacchini… - Journal of …, 2003 - Elsevier
Background: Proliferating cell nuclear antigen (PCNA) is a nuclear protein involved in DNA-
synthesis and repair. During DNA-synthesis and repair the only active PCNA fraction is …
synthesis and repair. During DNA-synthesis and repair the only active PCNA fraction is …
AgNOR area in interphase nuclei of human tumours correlates with the proliferative activity evaluated by bromodeoxyuridine labelling and Ki‐67 immunostaining
D Trerè, F Farabegoli, A Cancellieri… - The Journal of …, 1991 - Wiley Online Library
The area of silver‐stained proteins associated with interphase nucleolar organizer regions
(AgNORs) was compared with labelling data obtained by bromodeoxyuridine (BrdU) …
(AgNORs) was compared with labelling data obtained by bromodeoxyuridine (BrdU) …