User profiles for "author:J W Neal"
Jennifer Watling NealProfessor of Psychology, Michigan State University Verified email at msu.edu Cited by 4182 |
Dissecting metastasis using preclinical models and methods
JD Hebert, JW Neal, MM Winslow - Nature Reviews Cancer, 2023 - nature.com
Metastasis has long been understood to lead to the overwhelming majority of cancer-related
deaths. However, our understanding of the metastatic process, and thus our ability to …
deaths. However, our understanding of the metastatic process, and thus our ability to …
An ultrasensitive method for quantitating circulating tumor DNA with broad patient coverage
AM Newman, SV Bratman, J To, JF Wynne… - Nature medicine, 2014 - nature.com
Circulating tumor DNA (ctDNA) is a promising biomarker for noninvasive assessment of
cancer burden, but existing ctDNA detection methods have insufficient sensitivity or patient …
cancer burden, but existing ctDNA detection methods have insufficient sensitivity or patient …
[HTML][HTML] Long-term effects of Aβ42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial
Background Immunisation of patients with Alzheimer's disease with full-length amyloid-β
peptide (Aβ 42) can clear amyloid plaques from the brain. Our aim was to assess the relation …
peptide (Aβ 42) can clear amyloid plaques from the brain. Our aim was to assess the relation …
The multiple roles of the innate immune system in the regulation of apoptosis and inflammation in the brain
MR Griffiths, P Gasque, JW Neal - Journal of Neuropathology & …, 2009 - academic.oup.com
Central nervous system (CNS) tissues contain cells (ie glia and neurons) that have innate
immune functions. These cells express a range of receptors that are capable of detecting …
immune functions. These cells express a range of receptors that are capable of detecting …
Integrated digital error suppression for improved detection of circulating tumor DNA
High-throughput sequencing of circulating tumor DNA (ctDNA) promises to facilitate
personalized cancer therapy. However, low quantities of cell-free DNA (cfDNA) in the blood …
personalized cancer therapy. However, low quantities of cell-free DNA (cfDNA) in the blood …
Innate immunity and protective neuroinflammation: new emphasis on the role of neuroimmune regulatory proteins
M Griffiths, JW Neal, P Gasque - International review of neurobiology, 2007 - Elsevier
Brain inflammation due to infection, hemorrhage, and aging is associated with activation of
the local innate immune system as expressed by infiltrating cells, resident glial cells, and …
the local innate immune system as expressed by infiltrating cells, resident glial cells, and …
[HTML][HTML] Rociletinib in EGFR-Mutated Non–Small-Cell Lung Cancer
LV Sequist, JC Soria, JW Goldman… - … England Journal of …, 2015 - Mass Medical Soc
Background Non–small-cell lung cancer (NSCLC) with a mutation in the gene encoding
epidermal growth factor receptor (EGFR) is sensitive to approved EGFR inhibitors, but …
epidermal growth factor receptor (EGFR) is sensitive to approved EGFR inhibitors, but …
Early detection of molecular residual disease in localized lung cancer by circulating tumor DNA profiling
Identifying molecular residual disease (MRD) after treatment of localized lung cancer could
facilitate early intervention and personalization of adjuvant therapies. Here, we apply cancer …
facilitate early intervention and personalization of adjuvant therapies. Here, we apply cancer …
Integrating genomic features for non-invasive early lung cancer detection
Radiologic screening of high-risk adults reduces lung-cancer-related mortality,; however, a
small minority of eligible individuals undergo such screening in the United States,. The …
small minority of eligible individuals undergo such screening in the United States,. The …
[HTML][HTML] Circulating tumour DNA profiling reveals heterogeneity of EGFR inhibitor resistance mechanisms in lung cancer patients
JJ Chabon, AD Simmons, AF Lovejoy… - Nature …, 2016 - nature.com
Circulating tumour DNA (ctDNA) analysis facilitates studies of tumour heterogeneity. Here
we employ CAPP-Seq ctDNA analysis to study resistance mechanisms in 43 non-small cell …
we employ CAPP-Seq ctDNA analysis to study resistance mechanisms in 43 non-small cell …