The functions of some CLC Cl− channels are evident from human diseases that result from
their mutations, but the role of the broadly expressed ClC‐2 Cl− channel is less clear …

The cells responsible for production of the male sex hormone testosterone, the Leydig cells
of the testis, are post-mitotic cells with neuroendocrine characteristics. Their origin during …

Abstract BACKGROUND Tenascin‐C (TN‐C), a large extracellular matrix (ECM)
glycoprotein with a molecular weight of 180–250 kilodaltons, is present in several normal …

cells, and the testicular localization of the intermediate filament protein nestin, known to be
expressed in neural stem cells, by our group was the first step to define mural cells …

The transcription factor Pax6 has been implicated in neocortical neurogenesis in
vertebrates, including humans. Analyses of the role of Pax6 in layer formation and cognitive …

Previous studies have demonstrated that nitric oxide (NO) influences Leydig cell function.
Here we provide evidence for NO production and activity in seminiferous tubules and blood …

The lamina propria of human seminiferous tubules is composed of 5 to 7 cellular layers
separated by laminae of extracellular connective-tissue components. By means of …

The messenger molecule cyclic guanosine monophosphate (cGMP) is produced by different
isoforms of the enzyme guanylate cyclase (GC). Natriuretic peptides (ANP and CNP) bind to …

A number of marker substances for neuronal and neuroendocrine cells have been
demonstrated in the cytoplasm of the interstitial Leydig cells of human testes using basic …

The pericytes of the testis are part of the omnipresent population of pericytes in the
vertebrate body and are the only true pluripotent adult stem cells able to produce structures …