Right portal vein ligation combined with in situ splitting induces rapid left lateral liver lobe hypertrophy enabling 2-staged extended right hepatic resection in small-for …

…, R Hörbelt, A Kroemer, M Loss, P Rümmele… - Annals of …, 2012 - journals.lww.com
Objective: To evaluate a new 2-step technique for obtaining adequate but short-term
parenchymal hypertrophy in oncologic patients requiring extended right hepatic resection …

Minute gastric sclerosing stromal tumors (GIST tumorlets) are common in adults and frequently show c-KIT mutations

…, F Hofstaedter, H Blaszyk, P Rümmele… - The American journal …, 2007 - journals.lww.com
Multifocal hyperplasia of interstitial cells of Cajal (ICC hyperplasia) is a precursor of
hereditary gastrointestinal stromal tumors (GISTs) in patients with germline mutations of c …

The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma

…, KAT Silverstein, R Grützmann, D Aust, P Rümmele… - Nature, 2012 - nature.com
Pancreatic ductal adenocarcinoma (PDA) remains a lethal malignancy despite much
progress concerning its molecular characterization. PDA tumours harbour four signature …

Pegylated liposomal doxorubicin‐efficacy in patients with recurrent high‐grade glioma

…, K Fabel, U Baumgart, P Rümmele… - … Journal of the …, 2004 - Wiley Online Library
BACKGROUND Doxorubicin exhibits high efficacy in malignant glioma cell cultures.
Nonetheless, as a standard formulation, doxorubicin has not been used clinically, due to …

Extracellular citrate in health and disease

…, CH Wetzel, P Rümmele… - Current Molecular …, 2015 - ingentaconnect.com
Citrate is one of the major substrates for intracellular metabolism. The extracellular level of
citrate is stable in blood but varies locally, with slightly increased levels in brain and high …

[HTML][HTML] Google goes cancer: improving outcome prediction for cancer patients by network-based ranking of marker genes

…, J Roy, D Aust, T Knösel, P Rümmele… - PLoS computational …, 2012 - journals.plos.org
Predicting the clinical outcome of cancer patients based on the expression of marker genes
in their tumors has received increasing interest in the past decade. Accurate predictors of …

Update on sclerosing cholangitis in critically ill patients

GI Kirchner, P Rümmele - Viszeralmedizin, 2015 - karger.com
Background:‛ Sclerosing cholangitis in critically ill patients'(SC-CIP) is a cholestatic liver
disease of unknown etiology and represents the most prevalent form of secondary …

Ischemic-like cholangiopathy with secondary sclerosing cholangitis in critically ill patients

CM Gelbmann, P Rümmele, M Wimmer… - Official journal of the …, 2007 - journals.lww.com
OBJECTIVES Sclerosing cholangitis in critically ill patients (SC-CIP) is a newly described
entity of severe biliary disease with progression to liver cirrhosis. The mechanisms leading …

Glucose transporter 1 gene expression is related to thyroid neoplasms with an unfavorable prognosis: an immunohistochemical study

…, J Rüschoff, D Grimm, J Marienhagen, P Rümmele… - Thyroid, 2002 - liebertpub.com
Purpose: An accelerated rate of glucose metabolism mediated by overexpression of key
regulatory glycolytic enzymes and glucose transporters is among the most characteristic …

Analysis of intestinal haem-oxygenase-1 (HO-1) in clinical and experimental colitis

…, U Strauch, D Lochbaum, P Rümmele… - Clinical & …, 2005 - academic.oup.com
Summary Haem-oxygenase-1 (HO-1) has been shown to exert anti-inflammatory, anti-
apoptotic and anti-proliferative effects. We investigated HO-1 expression in patients with …